1521 disestablishments in North America

', also known as Mexico-Tenochtitlan', was a large Mexican in what is now the historic center of Mexico City. The exact date of the founding of the city is unclear, but the date 13 March 1325 was chosen in 1925 to celebrate the 600th anniversary of the city. The city was built on an island in what was then Lake Texcoco in the Valley of Mexico. The city was the capital of the expanding Aztec Empire in the 15th century until it was captured by the Tlaxcaltec and the Spanish in 1521.

former Mesoamerican empire

Mesoamerican civilization that flourished in the Valley of Oaxaca in Mesoamerica

altépetl or pre-Columbian city-state in central Mexico

former settlement in Guaynabo municipality, Puerto Rico