1536 establishments in South America

Valparaíso is a major city, commune, seaport, and naval base facility in the Valparaíso Region of Chile. Valparaíso was originally named after Valparaíso de Arriba, in Castile-La Mancha, Spain. With a population of 284,938, it is the 10th-largest commune in Chile.

Santiago de Cali (), or Cali, is the capital of the Valle del Cauca department, and the most populous city in southwest Colombia, with an estimated 2,280,522 residents in 2023. The city spans with of urban area, making Cali the second-largest city in the country by area and the third most populous. Cali is the main urban and economic center in the south of the country, and has one of Colombia's fastest-growing economies. The city was founded on 25 July 1536 by the Spanish explorer Sebastián de Belalcázar.