15th century in South America

1438–1533 empire in South America

papal bull by Alexander VI (4 May 1493) which granted to the Catholic Kings Ferdinand II of Aragon and Isabella I of Castile all lands to the "west and south" of a line 100 leagues west and south of any of the islands of the Azores or of Cape Verde

1471 battle between The Mapuche and Inca Empire

1420 earthquake and tsunami centered in northern Chile