1616 establishments in South America

Medellín ( ; or ), officially the Special District of Science, Technology and Innovation of Medellín (), is the second-largest city in Colombia after Bogotá, and the capital of the department of Antioquia. It is located in the Aburrá Valley, a central region of the Andes Mountains, in northwestern South America. The city's population was 2,427,129 at the 2018 census. The metro area of Medellín is the second-largest urban agglomeration in Colombia in terms of population and economy, with more than 4 million people.

Belém (; Portuguese for Bethlehem; initially called Nossa Senhora de Belém do Grão-Pará, in English Our Lady of Bethlehem of Great Pará), often called Belém of Pará, is the capital and largest city of the state of Pará in the north of Brazil. It is the gateway to the Amazon River with a busy port, airport, and bus/coach station. Belém lies approximately 100 km (62.1 miles) upriver from the Atlantic Ocean, on the Pará River, which is part of the greater Amazon River system, separated from the larger part of the Amazon delta by Ilha de Marajó (Marajo Island). With an estimated population of 1,39