Medieval Lesbos

The House of Gattilusio () was a Genoese noble family that ruled several lordships in the northern Aegean Sea between 1355 and 1462. Their rise began in 1354, when Francesco I Gattilusio assisted Emperor John V Palaiologos in regaining Constantinople from John VI Kantakouzenos. In 1355, Francesco married the emperor's sister Maria and received the island of Lesbos as a reward for his services against Kantakouzenos.

Byzantine nobleman and general

1462 conquest

Roman Catholic bishop