of course

adverb

Pronunciation: /əv ˈkɔːs/ / /əv ˈkɔɹs/ / /əv ˈkoə(ɹ)s/

That is part of ordinary behaviour or custom; customary, natural.
“Had Francesca grown up by his side, she would have loved him; and a thousand indulgences, the result of careless good-nature, would have linked the child to the parent, till the mutual affection would have become a thing of course.”
“I am not using a mere phrase of course, when I say that the feelings with which I bear a part in the ceremony of this day, are such as I find it difficult to utter in words.”

In due course; as a matter of course, as a natural result.
“He inspired love and emulation wherever he appeared; envy and jealous rage followed of course; so that he became a very desirable, though a very dangerous acquaintance.”
“Not tarrying long enough in the brain to be subject to reflection, the next sensations, of course, obliterate them.”
Naturally, as would be expected; for obvious reasons, obviously.
“Of course I know that!”
“You will of course surrender all your future rights to the property.”

Indicates enthusiastic agreement.
“Will you come with me? — Of course!”
Used to acknowledge thanks; ritual reply to “thank you”.
“Thank you! — Of course!”