Cephalosporin antibiotics

Cefcapene (INN) is a third-generation cephalosporin antibiotic.

Ceftiolene (INN) is a third-generation cephalosporin antibiotic.

Cefdaloxime (INN) is a third-generation cephalosporin antibiotic.

Ceftazidime/avibactam, sold under the brand name Avycaz (by AbbVie) among others, is a fixed-dose combination medication composed of ceftazidime, a cephalosporin antibiotic, and avibactam, a β-lactamase inhibitor. It is used to treat complicated intra-abdominal infections, urinary tract infections, and pneumonia. It is only recommended when other options are not appropriate. It is given by infusion into a vein.

Cefbuperazone (INN) is a second-generation cephalosporin antibiotic.

chemical compound

Cefuzonam (INN) is a second-generation cephalosporin antibiotic.

Cefoselis is a fourth generation cephalosporin. It is used extensively in Japan and China in the clinical treatment of various gram positive and gram negative infections. A 2014 study illustrated that Cefoselis is effective at treating respiratory and urinary tract infections.

Cefmatilen (INN, codenamed S-1090) is an orally-active cephalosporin antibiotic. It was developed in Japan and first described in 1992.

Cefluprenam is a fourth generation cephalosporin. It was patented in 2008 by now defunct Cubist Pharmaceuticals. A 1997 clinical trial illustrated that Cefluprenam is highly effective against bacterial pneumonia.

Nitrocefin is a chromogenic cephalosporin substrate routinely used to detect the presence of beta-lactamase enzymes produced by various microbes. Beta-lactamase mediated resistance to beta-lactam antibiotics such as penicillin is a widespread mechanism of resistance for a number of bacteria including members of the family Enterobacteriaceae, a major group of enteric Gram-negative bacteria. Other methods for beta-lactamase detection exist including PCR; however, nitrocefin allows for rapid beta-lactamase detection using few materials and inexpensive equipment.

Cefclidin (also known as cefclidin, cefaclidine, or E1040) is a cephalosporin antibiotic.