cefmatilen

Also known as S 1090

Cefmatilen (INN, codenamed S-1090) is an orally-active cephalosporin antibiotic. It was developed in Japan and first described in 1992.

In the Vinony graph

Vinony's link graph records 1 inbound reference to cefmatilen, and connects out to antibiotic, ceftolozane/tazobactam and bacteria.

It sits within the topics Cephalosporin antibiotics, Chemical pages without DrugBank identifier and Drugs not assigned an ATC code.

Vinony links it to 6 Wikipedia language editions.

Chemical data

Formula: C15H14N8O5S4
Molecular weight: 514.6 g/mol
IUPAC name: (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-hydroxyiminoacetyl]amino]-8-oxo-3-(2H-triazol-4-ylsulfanylmethylsulfanyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
SMILES: C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)/C(=N\O)/C3=CSC(=N3)N)C(=O)O)SCSC4=NNN=C4
InChIKey: UEQVTKSAEXANEZ-YCRCPZNHSA-N
XLogP: 1.3
Polar surface area: 304 Å²
H-bond donors: 5
H-bond acceptors: 14
Formal charge: 0

via PubChem

Wikidata facts

Subclass of: chemical compound
Mass: 513.9969995480001

Show 3 more facts

isomeric SMILES: C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)/C(=N\O)/C3=CSC(=N3)N)C(=O)O)SCSC4=NNN=C4
chemical formula: C₁₅H₁₄N₈O₅S₄
canonical SMILES: C1C(=C(N2C(S1)C(C2=O)NC(=O)C(=NO)C3=CSC(=N3)N)C(=O)O)SCSC4=NNN=C4

Sources (2)

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Encyclopedic overview

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Contents

References
Further reading

{{Drugbox | verifiedrevid = 443726531 | IUPAC_name = (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)- 2-(hydroxyimino)acetyl]amino}-8-oxo-3-{[(1H-1,2,3- triazol-4-ylsulfanyl)methyl]sulfanyl}-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | image = Cefmatilen.svg | image_class = skin-invert-image | width = 280

Excerpted from Wikipedia’s “cefmatilen” article, available under the CC BY-SA 4.0 licence.