Structure via PubChem · Public domain (PubChem)
1-ethynylcyclohexanol
Sign in to save1-Ethynylcyclohexanol (ECX) is an alkynyl alcohol derivative which is both a synthetic precursor to, and an active metabolite of the tranquilizer ethinamate, and has similar sedative, anticonvulsant and muscle relaxant effects. It has been sold as a designer drug, first being identified in the UK in March 2012.
Chemical data
- Formula
- C8H12O
- Molecular weight
- 124.18 g/mol
- IUPAC name
- 1-ethynylcyclohexan-1-ol
- SMILES
- C#CC1(CCCCC1)O
- InChIKey
- QYLFHLNFIHBCPR-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 20.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 124.089
Show 4 more facts
- canonical SMILES
- C#CC1(CCCCC1)O
- chemical formula
- C₈H₁₂O
- melting point
- 32.0
- Commons category
- 1-Ethynylcyclohexanol
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Preparation
- See also
- References
1-Ethynylcyclohexanol (ECX) is an alkynyl alcohol derivative which is both a synthetic precursor to, and an active metabolite of the tranquilizer ethinamate, and has similar sedative, anticonvulsant and muscle relaxant effects. It has been sold as a designer drug, first being identified in the UK in March 2012.
== Preparation == center|frameless|360x360px|Synthesis of 1-ethynylcyclohexanol from cyclohexanone. 1-Ethynylcyclohexanol can be prepared from cyclohexanone by reacting it with sodium acetylide in liquid ammonia, followed by an acidic work-up.
Excerpted from Wikipedia’s “1-ethynylcyclohexanol” article, available under the CC BY-SA 4.0 licence.