2-chloropyridine

Also known as alpha-chloropyridine, o-chloropyridine

2-Chloropyridine is an aryl chloride with the formula C5H4ClN. It is a colorless liquid that is mainly used to generate fungicides and insecticides in industry. It also serves to generate antihistamines and antiarrythymics for pharmaceutical purposes. It is one of three isomers of chloropyridine.

Chemical data

Formula: C5H4ClN
Molecular weight: 113.54 g/mol
IUPAC name: 2-chloropyridine
SMILES: C1=CC=NC(=C1)Cl
InChIKey: OKDGRDCXVWSXDC-UHFFFAOYSA-N
XLogP: 1.2
Polar surface area: 12.9 Å²
H-bond donors: 0
H-bond acceptors: 1
Formal charge: 0

via PubChem

Drug data · ChEMBL

Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: pyridine alkaloid
Mass: 113.003

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melting point: -46.0
chemical formula: C₅H₄ClN
canonical SMILES: C1=CC=NC(=C1)Cl
Commons category: 2-Chloropyridine

Sources (2)

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Encyclopedic overview

5 sections

Contents

Preparation
Main reactions and applications
Environmental properties
Toxicity
References

== Preparation == 500px| 2-Chloropyridine is produced by direct reaction of pyridine with chlorine. The initially formed 2-chloropyridine reacts further to give 2,6-dichloropyridine.

Excerpted from Wikipedia’s “2-chloropyridine” article, available under the CC BY-SA 4.0 licence.