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acetyl coenzyme A

Structure via PubChem · Public domain (PubChem)

EntityQ715317· pop 40· linked from 1,723 articles

acetyl coenzyme A

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Also known as acetyl-CoA, acetylCoA, S-acetyl coenzyme A, S-acetyl-coenzyme A, S-acetyl-CoA, AcCoA

Chemical data

Formula
C23H38N7O17P3S
Molecular weight
809.6 g/mol
IUPAC name
S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] ethanethioate
SMILES
CC(=O)SCCNC(=O)CCNC(=O)[C@@H](C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O
InChIKey
ZSLZBFCDCINBPY-ZSJPKINUSA-N
XLogP
-5.6
Polar surface area
389 Ų
H-bond donors
9
H-bond acceptors
22
Formal charge
0

via PubChem

~12 min read

Encyclopedic overview

9 sections
Contents
  • Role
  • Biosynthesis
  • Extramitochondrial
  • Intramitochondrial
  • Functions
  • Intermediates in various pathways
  • See also
  • References
  • External links

{{chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 477240040 | Name = Acetyl-CoA | ImageFile = Acetyl-CoA-2D_colored.svg | ImageClass= skin-invert-image | ImageSize = 320 | ImageFile2 = Acetyl-CoA-3D-balls.png | ImageSize2 = 320 | ImageFile3 = Acetyl-CoA-3D-vdW.png | ImageSize3 = 320 | PIN = O1-{(3R)-4-[(3-{[2-(Acetylsulfanyl)ethyl]amino}-3-oxopropyl)amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl} O3-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methyl} dihydrogen diphosphate | OtherNames = | Section1 = | Section2 = | Section3 = | Section4 = | Section5 = | Section6 = }}

Acetyl-CoA (acetyl coenzyme A) is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism. Its main function is to deliver the acetyl group to the citric acid cycle (Krebs cycle) to be oxidized for energy production.

Excerpted from Wikipedia’s “acetyl coenzyme A” article, available under the CC BY-SA 4.0 licence.

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