Skip to content
advantame

Structure via PubChem · Public domain (PubChem)

EntityQ16886625· pop 7· linked from 73 articles

Also known as advantame anhydrous, N-[N-[3-(3-hydroxy-4-methoxyphenyl)propyl]-α-L-aspartyl]-L-phenylalanine 1-methyl ester

Advantame is a non-caloric artificial sweetener and aspartame analog by Ajinomoto. By mass, it is about 20,000 times sweeter than sucrose and about 110 times sweeter than aspartame. It has no notable off-flavors when compared to sucrose and tastes sweet a bit longer than aspartame and is chemically more stable. It can be blended with many other natural and artificial sweeteners.

Chemical data

Formula
C24H30N2O7
Molecular weight
458.5 g/mol
IUPAC name
(3S)-3-[3-(3-hydroxy-4-methoxyphenyl)propylamino]-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
SMILES
COC1=C(C=C(C=C1)CCCN[C@@H](CC(=O)O)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)OC)O
InChIKey
YTKBWWKAVMSYHE-OALUTQOASA-N
XLogP
0.2
Polar surface area
134 Ų
H-bond donors
4
H-bond acceptors
8
Formal charge
0

via PubChem

Wikidata facts

Mass
458.205
Show 5 more facts
chemical formula
C₂₄H₃₀N₂O₇
canonical SMILES
COC1=C(C=C(C=C1)CCCNC(CC(=O)O)C(=O)NC(CC2=CC=CC=C2)C(=O)OC)O
isomeric SMILES
COC1=C(C=C(C=C1)CCCN[C@@H](CC(=O)O)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)OC)O
Commons category
Advantame
melting point
101.5
Sources (3)

via Wikidata · CC0

~6 min read

Encyclopedic overview

8 sections
Contents
  • Safety
  • Sweetness
  • Chemistry
  • Metabolism
  • History
  • Notes
  • References
  • External links

{{Chembox

| Name = Advantame | ImageFile = Advantame Structural Formula V.1.svg | ImageClass = skin-invert-image | IUPACName = Methyl N-[3-(3-Hydroxy-4-methoxyphenyl)propyl]aspartylphenylalaninate | SystematicName = (3S)-3-{[3-(3-Hydroxy-4-methoxyphenyl)propyl]amino}-4-{[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino}-4-oxobutanoic acid | OtherNames = N-[N-[3-(3-Hydroxy-4-methoxyphenyl)propyl]-α-L-aspartyl]-L-phenylalanine 1-methyl ester | Section1 = | Section2 = | Section3 = }}

Excerpted from Wikipedia’s “advantame” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0