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ageing
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Ageing (or aging in American English) is the process of becoming older. The term refers mainly to humans, many other animals, and fungi; whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In a broader sense, ageing can refer to single cells within an organism which have ceased dividing, or to the population of a species.
Ageing is the biological process of becoming older, which occurs in humans, many animals, and fungi, though some organisms like bacteria and certain plants can potentially live indefinitely. Understanding ageing matters because it affects how bodies and populations change over time, though the underlying reasons why most living things age remain an important area of study.
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Research
744,801 papers- From discoveries in ageing research to therapeutics for healthy ageing.ReviewNature · 2019Campisi J, Kapahi P, Lithgow GJ et al.DOI: 10.1038/s41586-019-1365-2
- Ageing as a risk factor for neurodegenerative disease.ReviewNature reviews. Neurology · 2019Hou Y, Dan X, Babbar M et al.DOI: 10.1038/s41582-019-0244-7
- An overview of contemporary theories of ageing.ReviewNature cell biology · 2025de Magalhães JPDOI: 10.1038/s41556-025-01698-7
- The Hallmarks of Ageing in Microglia.ReviewCellular and molecular neurobiology · 2025Carr L, Mustafa S, Collins-Praino LEDOI: 10.1007/s10571-025-01564-y
- Ageing-associated phenotypes in mice.ReviewMechanisms of ageing and development · 2023Xie K, Ehninger DDOI: 10.1016/j.mad.2023.111852
- Healthy ageing, resilience and wellbeing.Epidemiology and psychiatric sciences · 2017Cosco TD, Howse K, Brayne CDOI: 10.1017/S2045796017000324
- Ageing and Cognition.ReviewSub-cellular biochemistry · 2019Juan SMA, Adlard PADOI: 10.1007/978-981-13-3681-2_5
- MDSCs, ageing and inflammageing.ReviewCellular immunology · 2021Pawelec G, Picard E, Bueno V et al.DOI: 10.1016/j.cellimm.2021.104297
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~40 min read
Article
23 sectionsContents
- Ageing versus immortality
- Symptoms
- Biological basis
- Programmed factors
- Midlife Acceleration
- Evolution of ageing
- Damage-related factors
- Research
- Diet
- Exercise
- Social factors
- Society and culture
- Economics
- Sociology
- Health care demand
- Self-perception
- Healthy ageing
- Intrinsic capacity
- Superaging
- Successful ageing
- Education and ageing
- See also
- References
Ageing (or aging in American English) is the process of becoming older. The term refers mainly to humans, many other animals, and fungi; whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In a broader sense, ageing can refer to single cells within an organism which have ceased dividing, or to the population of a species.
In humans, ageing represents the accumulation of changes in a human being over time and can encompass physical, psychological, and social changes. Reaction time, for example, may slow with age, while memories and general knowledge typically increase. Of the roughly 150,000 people who die each day across the globe, about two-thirds die from age-related causes.
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