AMOTL2
Sign in to saveAlso known as LCCP, angiomotin like 2
Angiomotin-like protein 2 is a protein that in humans is encoded by the AMOTL2 gene.
Gene data
AMOTL2- Name
- angiomotin like 2
- Type
- protein-coding
- Position
- 134,355,347–134,375,479 (−)
- Aliases
- LCCP
- Ensembl
- ENSG00000114019
- RefSeq RNA
- NM_001278683.1, NM_001278685.2, NM_001363943.2, NM_016201.4
- RefSeq protein
- NP_001265612.1, NP_001265614.1, NP_001350872.1, NP_057285.3
Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
angiomotin like 2
- Symbol
- AMOTL2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:134,355,347-134,375,479
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Angiomotin-like protein 2 is a protein that in humans is encoded by the AMOTL2 gene.
Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motins protein family.
Excerpted from Wikipedia’s “AMOTL2” article, available under the CC BY-SA 4.0 licence.