andrographolide

Andrographolide is a labdane diterpenoid that has been isolated from the stem and leaves of Andrographis paniculata. Andrographolide is an extremely bitter substance.

Research

1,824 papers

Andrographolide: A review of its pharmacology, pharmacokinetics, toxicity and clinical trials and pharmaceutical researches.Phytotherapy research : PTR · 2022
Andrographolide: Synthetic Methods and Biological Activities.Mini reviews in medicinal chemistry · 2020
Andrographolide: A Review of Analytical Methods.Journal of chromatographic science · 2021
Andrographolide: Chemical modification and its effect on biological activities.Bioorganic chemistry · 2020
Andrographolide alleviates Parkinsonism in MPTP-PD mice via targeting mitochondrial fission mediated by dynamin-related protein 1.British journal of pharmacology · 2019

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Wikidata facts

Mass: 350.2093240599999

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canonical SMILES: O=C3OCC(O)C3=CCC1\C(=C)CCC2C(C)(CO)C(O)CCC12C
chemical formula: C₂₀H₃₀O₅
isomeric SMILES: C[C@@]12CC[C@H]([C@@]([C@H]1CCC(=C)[C@H]2C/C=C/3[C@@H](COC3=O)O)(C)CO)O

Sources (3)

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Article

4 sections

Contents

Biosynthesis
Research
See also
References

Andrographolide is a labdane diterpenoid that has been isolated from the stem and leaves of Andrographis paniculata. Andrographolide is an extremely bitter substance.

Andrographolide has been studied for its effects on cell signaling, immunomodulation, and stroke. Study has shown that andrographolide may bind to a spectrum of protein targets including NF-κB and actin by covalent modification.