ATL1

Also known as AD-FSP, FSP1, GBP3, HSN1D, SPG3, SPG3A, atlastin1, Atlastin

Atlastin-1, is a protein that in humans is encoded by the ATL1 gene.

In the Vinony graph

Within Vinony's link graph, ATL1 is referenced by 4 other articles, and connects out to Q180686, human chromosome 14 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 14.

Its subject is documented across 5 Wikipedia language editions.

Gene data

ATL1

Name: atlastin GTPase 1
Type: protein-coding
Position: 50,532,509–50,634,017 (+)
Aliases: AD-FSP, ATL-1, FSP1, HSN1D, SPG3, SPG3A, atlastin1
Ensembl: ENSG00000198513
RefSeq RNA: NM_001127713.1, NM_015915.5, NM_181598.4, XM_047431430.1, XM_054376164.1
RefSeq protein: NP_001121185.1, NP_056999.2, NP_853629.2, XP_047287386.1, XP_054232139.1

The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].