برکتانت
Sign in to saveAlso known as Survanta
Beractant, also known by the trade name of Survanta, is a modified bovine pulmonary surfactant containing bovine lung extract (phospholipids, neutral lipids, fatty acids, and bovine surfactant proteins), to which synthetic DPPC, tripalmitin and palmitic acid are added. The composition provides 25 mg/mL phospholipids, 0.5 to 1.75 mg/mL triglycerides, 1.4 to 3.5 mg/mL free fatty acids, and <1.0 mg/mL total surfactant proteins. As an intratracheal suspension, it can be used for the prevention and treatment of neonatal respiratory distress syndrome. Survanta is manufactured by
Chemical data
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Unknown
- First approval
- 1991
- Admin. routes
- parenteral
- Indications
- newborn respiratory distress syndrome, acute respiratory distress syndrome, lung disease
via ChEMBL · EBI
Research
377 papers- Beractant and poractant alfa in premature neonates with respiratory distress syndrome: a systematic review of real-world evidence studies and randomized controlled trials.Journal of perinatology : official journal of the California Perinatal Association · 2020
- Comparative effectiveness of calfactant and beractant in neonatal respiratory distress syndrome: A systemic review and meta-analysis.Pediatric pulmonology · 2022
- Less Invasive Surfactant Administration: A Review of Current Evidence of Clinical Outcomes With Beractant.Cureus · 2022
- Comparison of Efficacy of Beractant (SURVANTA®) and Poractant Alfa (CUROSURF®) in Preterm Infants With Respiratory Distress Syndrome in Tawam Hospital, Al Ain, UAE: A Retrospective Study.Cureus · 2024
- Comparison of Beractant Administration by Thin Catheter vs Intubation-Surfactant-Extubation (INSURE) in Preterm Infants Less than 34 Weeks Gestational Age with Respiratory Distress Syndrome - A Single Centre Experience.Journal of neonatal-perinatal medicine · 2023
via PubMed
Wikidata facts
- Instance of
- medication
Show 3 more facts
- NCI Thesaurus ID
- C81354
- subject has role
- pulmonary surfactant
- medical condition treated
- acute respiratory distress syndrome
Sources (1)
via Wikidata · CC0