Structure via PubChem · Public domain (PubChem)
beta-bungarotoxin
Sign in to saveβ-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait (Bungarus multicinctus) venoms. It is the prototypic class of snake β-neurotoxins. There are at least five isoforms, coded β1 to β5, assembled from different combinations of A and Bchains.
In the Vinony graph
Within Vinony's link graph, beta-bungarotoxin is referenced by 408 other articles, and connects out to botulinum toxin group, solasonine and lipopolysaccharide.
It sits within the topics Acetylcholine release inhibitors, Bungarus and Ion channel toxins.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C50H70O14
- Molecular weight
- 895.1 g/mol
- IUPAC name
- 2-[[(1R,3S,5R,7S,9R,11S,12S,14S,16R,18S,20R,24S,26R,28S,30R,31R,33S,35R,37S,42R,44S,46R,48S)-12-hydroxy-1,3,11,24,31,41,44-heptamethyl-39-oxo-2,6,10,15,19,25,29,34,38,43,47-undecaoxaundecacyclo[26.22.0.03,26.05,24.07,20.09,18.011,16.030,48.033,46.035,44.037,42]pentaconta-21,40-dien-14-yl]methyl]prop-2-enal
- SMILES
- C[C@@H]1C[C@H]2[C@@H](C[C@]3([C@H](O2)C[C@H]4[C@H](O3)C(=CC(=O)O4)C)C)O[C@@H]5[C@@H]1O[C@H]6C[C@@H]7[C@](C[C@@H]8[C@@](O7)(CC=C[C@@H]9[C@@H](O8)C[C@@H]1[C@@H](O9)C[C@@H]2[C@@](O1)([C@H](C[C@@H](O2)CC(=C)C=O)O)C)C)(O[C@@]6(CC5)C)C
- InChIKey
- LYTCVQQGCSNFJU-PJLYXUTNSA-N
- XLogP
- 3.7
- Polar surface area
- 156 Ų
- H-bond donors
- 1
- H-bond acceptors
- 14
- Formal charge
- 0
via PubChem
Wikidata facts
- Has part
- carbon
- Mass
- 894.4765569200001
Show 4 more facts
- isomeric SMILES
- C=C(C=O)C[C@H]1C[C@H](O)[C@]2(C)O[C@@H]3C[C@@H]4O[C@@H]5C[C@]6(C)O[C@]7(C)CC[C@@H]8O[C@@H]9C[C@]%10(C)O[C@@H]%11C(C)=CC(=O)O[C@H]%11C[C@H]%10O[C@H]9C[C@@H](C)[C@H]8O[C@H]7C[C@H]6O[C@@]5(C)CC=C[C@H]4O[C@H]3C[C@H]2O1
- chemical formula
- C₅₀H₇₀O₁₄
- canonical SMILES
- C=C(C=O)CC1CC(O)C2(C)OC3CC4OC5CC6(C)OC7(C)CCC8OC9CC%10(C)OC%11C(C)=CC(=O)OC%11CC%10OC9CC(C)C8OC7CC6OC5(C)CC=CC4OC3CC2O1
- stereoisomer of
- alpha-bungarotoxin
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Binding sites
- See also
- References
β-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait (Bungarus multicinctus) venoms. It is the prototypic class of snake β-neurotoxins. There are at least five isoforms, coded β1 to β5, assembled from different combinations of A and Bchains.
The toxin is a heterodimer of two chains. The A chain confers phospholipase A2 (PLP A2) activity, and the B chain, like dendrotoxins, have a Kunitz domain. There are many isoforms of these chains: examples of A chains include A1 (), A3 (), and A4 (), and examples of B chains include B2 () and B3 (). The B chain plays a functional role in inducing apoptosis.
Excerpted from Wikipedia’s “beta-bungarotoxin” article, available under the CC BY-SA 4.0 licence.