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right|thumb|Ophiognomonia clavigignenti-juglandacearum|Butternut canker is a lethal disease of butternut trees, and has no cure.

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right|thumb|Ophiognomonia clavigignenti-juglandacearum|Butternut canker is a lethal disease of butternut trees, and has no cure.

A plant canker is a small area of dead tissue, which grows slowly, often over years. Some cankers are of only minor consequence, but others are ultimately lethal and therefore can have major economic implications for agriculture and horticulture. Their causes include a wide range of organisms such as fungi, bacteria, mycoplasmas and viruses. The majority of canker-causing organisms are bound to a unique host species or genus, but a few will attack other plants. Weather (via frost or windstorm damage) and animal damage can also cause stress to the plant resulting in cankers. Other causes of cankers is pruning when the bark is wet or using un-sterilized tools.

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