Structure via PubChem · Public domain (PubChem)
citraconic acid
Sign in to saveAlso known as (2E)-2-METHYLBUT-2-ENEDIOIC ACID, cis-Methylbutenedioic acid, Citraconate, METHYLMALEIC ACID, trans-2-Methyl-2-butenedioic acid, Methylmaleate, (Z)-2-Methyl-2-butenedioate, 2-Methyl-2-butenedioic acid
chemical compound
In the Vinony graph
Within Vinony's link graph, citraconic acid is referenced by 10 other articles, and connects out to International Standard Book Number, mass density and digital object identifier.
It is catalogued under topics including Chembox having GHS data, Dicarboxylic acids and ECHA InfoCard ID from Wikidata.
Its subject is documented across 13 Wikipedia language editions.
Chemical data
- Formula
- C5H6O4
- Molecular weight
- 130.1 g/mol
- IUPAC name
- (Z)-2-methylbut-2-enedioic acid
- SMILES
- C/C(=C/C(=O)O)/C(=O)O
- InChIKey
- HNEGQIOMVPPMNR-IHWYPQMZSA-N
- XLogP
- -0.1
- Polar surface area
- 74.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
128 papers- Growth hormone combined with estrogen improves intrauterine adhesion fibrosis by downregulating endometrial microbial citraconic acid to target β-catenin protein.mSystems · 2025
- Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism.Nature metabolism · 2022
- Aconitate decarboxylase (ACOD1) has found a disease.Trends in endocrinology and metabolism: TEM · 2024
- Citraconic acid mitigates radiation-induced intestinal injury by modulating IL-17 signaling to enhance epithelial regeneration.BMC gastroenterology · 2026
- pH-Responsive Charge-Conversion Progelator Peptides.Advanced functional materials · 2021
via PubMed
Wikidata facts
- Subclass of
- dicarboxylic acid
- Mass
- 130.027
Show 6 more facts
- pKa
- 2.42
- chemical formula
- C₅H₆O₄
- melting point
- 90
- isomeric SMILES
- C/C(=C/C(=O)O)/C(=O)O
- canonical SMILES
- CC(=CC(=O)O)C(=O)O
- Commons category
- Citraconic acid
via Wikidata · CC0
Connections
International Standard Book Number
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mass density
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digital object identifier
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chemical formula
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melting point
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organic compound
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alkene
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citric acid
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molar mass
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CAS Registry Number
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PubChem
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aqueous solution
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cis–trans isomerism
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simplified molecular input line entry specification
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ChemSpider
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DrugBank
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International Chemical Identifier
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Kyoto Encyclopedia of Genes and Genomes
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European Chemicals Agency
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Globally Harmonized System of Classification and Labelling of Chemicals
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