CSRP1

Also known as CRP, CRP1, CSRP, CYRP, D1S181E, HEL-141, HEL-S-286, cysteine and glycine rich protein 1

Cysteine and glycine-rich protein 1 is a protein that in humans is encoded by the CSRP1 gene.

Gene data

CSRP1

Name: cysteine and glycine rich protein 1
Type: protein-coding
Position: 201,483,530–201,513,100 (−)
Aliases: CRP, CRP1, CSRP, CYRP, D1S181E, HEL-141, HEL-S-286
Ensembl: ENSG00000159176
RefSeq RNA: NM_001144773.1, NM_001193570.2, NM_001193571.2, NM_001193572.2, NM_004078.3
RefSeq protein: NP_001180499.1, NP_001180500.1, NP_001180501.1, NP_004069.1

This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010].

Gene Ontology

Biological process

sarcomere organization muscle tissue development platelet aggregation

Molecular function

RNA binding protein binding zinc ion binding structural constituent of muscle actinin binding

Cellular component

nucleus nucleus nucleus cytoplasm focal adhesion Z disc extracellular exosome

Pathways

MTF1 activates gene expression Response to metal ions Cellular responses to stimuli MECP2 and Associated Rett Syndrome VEGFA-VEGFR2 Signaling Pathway

via MyGene.info

Gene · Ensembl

cysteine and glycine rich protein 1

Symbol: CSRP1
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:201,483,530-201,540,142
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein CSRP1 PDB 1ctl.png

Show 5 more facts

HomoloGene ID: 37874
exact match: identifiers.org/ncbigene/1465
genomic end: 201478584
genomic start: 201452658
cytogenetic location: 1q32.1

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Cysteine and glycine-rich protein 1 is a protein that in humans is encoded by the CSRP1 gene.

CSRP1 is a member of the CSRP family of genes encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in CRP1 is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation Other genes in the family include CSRP2 and CSRP3.