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cyproconazole

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EntityQ1148372· pop 7· linked from 10 articles

cyproconazole

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Also known as 2-(4-Chlorophenyl)-3-cyclopropyl-1-(1,2,4-triazol-1-yl)butan-2-ol, 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

Cyproconazole is an agricultural fungicide of the class of azoles, used on cereal crops, coffee, sugar beet, fruit trees and grapes, and peanuts, on sod farms and golf course turf and on wood as a preservative. It has been used against powdery mildew, rust on cereals and apple scab, and applied by air or on the ground or by chemigation.

Chemical data

Formula
C15H18ClN3O
Molecular weight
291.77 g/mol
IUPAC name
2-(4-chlorophenyl)-3-cyclopropyl-1-(1,2,4-triazol-1-yl)butan-2-ol
SMILES
CC(C1CC1)C(CN2C=NC=N2)(C3=CC=C(C=C3)Cl)O
InChIKey
UFNOUKDBUJZYDE-UHFFFAOYSA-N
XLogP
2.9
Polar surface area
50.9 Ų
H-bond donors
1
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
291.114
Has use
fungicide
Show 2 more facts
chemical formula
C₁₅H₁₈ClN₃O
canonical SMILES
CC(C1CC1)C(CN2C=NC=N2)(C3=CC=C(C=C3)Cl)O
Sources (2)

via Wikidata · CC0

~6 min read

Encyclopedic overview

11 sections
Contents
  • Mechanism of action
  • Use
  • Formulations
  • Application
  • Hazards and ecotoxicity
  • Toxicokinetics
  • Fungal resistance
  • Regulation
  • Europe
  • References
  • External links

Cyproconazole is an agricultural fungicide of the class of azoles, used on cereal crops, coffee, sugar beet, fruit trees and grapes, and peanuts, on sod farms and golf course turf and on wood as a preservative. It has been used against powdery mildew, rust on cereals and apple scab, and applied by air or on the ground or by chemigation.

In the US approval began in 1993, and it was introduced to the market by then Sandoz in 1994, which as of 2000 has been Syngenta. EU approval began in June 2011 and expired after 10 years in May 2021. It is persistent in both soil and water systems. The European Community has classified cyproconazole into carcinogen category 3 as limited evidence, as reproductive toxicant, and as dangerous for the environment, because very toxic to aquatic organisms, causing acute and long-term adverse effects in the aquatic environment. While it is moderately toxic to mammals and most aquatic organisms, earthworms and honeybees, it is highly toxic to birds.

Excerpted from Wikipedia’s “cyproconazole” article, available under the CC BY-SA 4.0 licence.

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