دانترون

Chemical data

Formula

C14H8O4

Molecular weight

240.21 g/mol

IUPAC name

1,8-dihydroxyanthracene-9,10-dione

SMILES

C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O

InChIKey

QBPFLULOKWLNNW-UHFFFAOYSA-N

XLogP

3.2

Polar surface area

74.6 Ų

H-bond donors

2

H-bond acceptors

4

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

Indications

Constipation

via ChEMBL · EBI

• Danthron attenuates experimental atherosclerosis by targeting foam cell formation.Experimental physiology · 2021
• Danthron.Report on carcinogens : carcinogen profiles · 2011
• Laxatives: replacing danthron.Drug and therapeutics bulletin · 1988
• Danthron suppresses autophagy and sensitizes pancreatic cancer cells to doxorubicin.Toxicology in vitro : an international journal published in association with BIBRA · 2019
• Danthron, an Anthraquinone Isolated from a Marine Fungus, Is a New Inhibitor of Angiogenesis Exhibiting Interesting Antitumor and Antioxidant Properties.Antioxidants (Basel, Switzerland) · 2023

via PubMed

Wikidata facts

Mass

240.042

Has use

medication

via Wikidata · CC0