dichlofenthion
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- Mass
- 313.97
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- chemical formula
- C₁₀H₁₃Cl₂O₃PS
- canonical SMILES
- CCOP(=S)(OCC)OC1=C(C=C(C=C1)Cl)Cl
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Article
38 sectionsContents
- Introduction and History
- Structure Reactivity Synthesis
- Structure
- Reactivity
- Synthesis
- Metabolism / Biotransformation
- Phase I reaction
- Phase II reaction
- Use/Purpose, Availability, Efficacy
- Detailed Uses
- Availability
- Efficacy
- Molecular mechanism of action
- Breakdown of Molecular Mechanism of Action of Dichlofenthion
- Delayed onset poisoning
- Possible treatments
- Recovery from inhibition
- Atropine
- Pralidoxime (2-PAM)
- Supportive care
- Decontamination
- Monitoring and observation
- Toxicology Data
- LD50 (Lethal Dose 50)
- LC50 (Lethal Concentration 50)
- NOAEL (no observed adverse effect level)
- LOAEL (lowest observed adverse effect level)
- Side/Adverse Effects
- Environmental and Health Impact
- Environmental fate
- Ecotoxicity
- Health
- Muscarinic effects
- Nicotinic effects
- Carcinogenicity
- Reproductive toxicity
- Germ cell mutagenicity
- References
== Introduction and History == Dichlofenthion (IUPAC name: O-(2,4-dichlorophenyl) O,O-diethyl phosphorothioate) is a fat-soluble organophosphorus compound primarily used in agricultural practices as a pesticide and nematicide to control a variety of insect pests. Organophosphates as a class were initially developed in the early 20th century, with some of the earliest compounds being synthesized as potential chemical warfare agents during and after World War I. However, their potent action on the nervous system quickly led to their adoption in agriculture to control pests that affect crops. Until the 21st century, they were among the most widely used insecticides available. Dichlofenthion emerged in the mid-20th century as part of the search for more effective and selective insecticides that could provide better crop protection with reduced environmental and health impacts.
== Structure Reactivity Synthesis ==