Structure via PubChem · Public domain (PubChem)
dichloroacetic acid
Sign in to saveAlso known as DCA, dichloracetic acid, dichloroacetate, 2,2-dichloroacetic acid, bichloracetic acid
chemical compound
In the Vinony graph
Within Vinony's link graph, dichloroacetic acid is referenced by 95 other articles, and connects out to mitochondrion, alternative medicine and precipitation.
It sits within the topics Acetic acids, Alternative cancer treatments and Chembox having GHS data.
Its subject is documented across 28 Wikipedia language editions.
Chemical data
- Formula
- C2H2Cl2O2
- Molecular weight
- 128.94 g/mol
- IUPAC name
- 2,2-dichloroacetic acid
- SMILES
- C(C(=O)O)(Cl)Cl
- InChIKey
- JXTHNDFMNIQAHM-UHFFFAOYSA-N
- XLogP
- 0.9
- Polar surface area
- 37.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- glioblastoma multiforme, neoplasm, head and neck malignant neoplasia, Hyperglycemia
via ChEMBL · EBI
Research
1,784 papers- Dichloroacetic acid.IARC monographs on the evaluation of carcinogenic risks to humans · 1995
- Cytotoxic derivatives of dichloroacetic acid and some metal complexes.Archiv der Pharmazie · 2022
- Dichloroacetic acid and rapamycin synergistically inhibit tumor progression.Journal of Zhejiang University. Science. B · 2023
- Dichloroacetic acid and trichloroacetic acid as disinfection by-products in drinking water are endocrine-disrupting chemicals.Journal of hazardous materials · 2024
- Dichloroacetic Acid Enhances Photodynamic Therapy-Induced Regulated Cell Death in PANC-1 Pancreatic Cancer Cell Line.International journal of molecular sciences · 2025
via PubMed
Wikidata facts
- Has part
- chlorine
- Mass
- 127.943
Show 7 more facts
- chemical formula
- C₂H₂Cl₂O₂
- canonical SMILES
- C(C(=O)O)(Cl)Cl
- Commons category
- Dichloroacetic acid
- pKa
- 1.30
- melting point
- 13.5
- found in taxon
- Asparagopsis taxiformis
- subject has role
- carcinogen
via Wikidata · CC0
~10 min read
Encyclopedic overview
Names
Preferred IUPAC name Dichloroacetic acid
Excerpted from Wikipedia’s “dichloroacetic acid” article, available under the CC BY-SA 4.0 licence.
Connections
mitochondrion
Entity
alternative medicine
Entity
precipitation
Entity
peripheral neuropathy
Entity
energy medicine
Entity
Cansema
Entity
atom
Entity
grape
Entity
protein
Entity
chlorine
Entity
International Standard Book Number
Entity
germanium
Entity
enzyme
Entity
metabolism
Entity
ethanol
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fasting
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mass density
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salt
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drug
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halogens
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