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DiOC6
Sign in to saveAlso known as 3,3′-dihexyloxacarbocyanine iodide
DiOC6 (3,3′-dihexyloxacarbocyanine iodide) is a fluorescent dye used for the staining of a cell's endoplasmic reticulum, vesicle membranes and mitochondria. Binding to these structures occurs via the dye's hydrophilic groups. DiOC6 can be used to label living cells, however they are quickly damaged due to the dye's extreme phototoxicity, so cells stained with this dye can only be exposed to light for short periods of time. When exposed to blue light, the dye fluoresces green.
Chemical data
- Formula
- C29H37IN2O2
- Molecular weight
- 572.5 g/mol
- IUPAC name
- (2Z)-3-hexyl-2-[(E)-3-(3-hexyl-1,3-benzoxazol-3-ium-2-yl)prop-2-enylidene]-1,3-benzoxazole iodide
- SMILES
- CCCCCCN\1C2=CC=CC=C2O/C1=C\C=C\C3=[N+](C4=CC=CC=C4O3)CCCCCC.[I-]
- InChIKey
- XVLXYDXJEKLXHN-UHFFFAOYSA-M
- Polar surface area
- 29.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 572.189976
Show 3 more facts
- chemical formula
- C₂₉H₃₇IN₂O₂
- canonical SMILES
- CCCCCCN1C2=CC=CC=C2OC1=CC=CC3=[N+](C4=CC=CC=C4O3)CCCCCC.[I-]
- isomeric SMILES
- CCCCCCN\1C2=CC=CC=C2O/C1=C\C=C\C3=[N+](C4=CC=CC=C4O3)CCCCCC.[I-]
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
DiOC6 (3,3′-dihexyloxacarbocyanine iodide) is a fluorescent dye used for the staining of a cell's endoplasmic reticulum, vesicle membranes and mitochondria. Binding to these structures occurs via the dye's hydrophilic groups. DiOC6 can be used to label living cells, however they are quickly damaged due to the dye's extreme phototoxicity, so cells stained with this dye can only be exposed to light for short periods of time. When exposed to blue light, the dye fluoresces green.
==See also== DiI
Excerpted from Wikipedia’s “DiOC6” article, available under the CC BY-SA 4.0 licence.