Structure via PubChem · Public domain (PubChem)
dyspropterin
Sign in to saveAlso known as 6-pyruvoyl-5,6,7,8-tetrahydropterin, 6-pyruvoyltetrahydropterin, 6-PTHB, PTP
Dyspropterin (6-pyruvoyltetrahydropterin, 6-PTHB) is an intermediate in tetrahydrobiopterin biosynthesis. It is the product of the enzyme 6-pyruvoyltetrahydropterin synthase and the substrate of two enzymes, 6-pyruvoyltetrahydropterin 2'-reductase and sepiapterin reductase.
Chemical data
- Formula
- C9H11N5O3
- Molecular weight
- 237.22 g/mol
- IUPAC name
- 1-(2-amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)propane-1,2-dione
- SMILES
- CC(=O)C(=O)C1CNC2=C(N1)C(=O)N=C(N2)N
- InChIKey
- WBJZXBUVECZHCE-UHFFFAOYSA-N
- XLogP
- -1.7
- Polar surface area
- 126 Ų
- H-bond donors
- 4
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 237.086189
Show 4 more facts
- subject has role
- primary metabolite
- chemical formula
- C₉H₁₁N₅O₃
- canonical SMILES
- CC(=O)C(=O)C1CNC2=C(N1)C(=O)N=C(N2)N
- found in taxon
- Homo sapiens
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Dyspropterin (6-pyruvoyltetrahydropterin, 6-PTHB) is an intermediate in tetrahydrobiopterin biosynthesis. It is the product of the enzyme 6-pyruvoyltetrahydropterin synthase and the substrate of two enzymes, 6-pyruvoyltetrahydropterin 2'-reductase and sepiapterin reductase.
Dyspropterin exists in all living organisms, ranging from bacteria to humans. Dyspropterin has been detected, but not quantified in, a few different foods, such as ducks (Anatidae), chickens (Gallus gallus), and domestic pigs (Sus scrofa domestica). This could make dyspropterin a potential biomarker for the consumption of these foods.
Excerpted from Wikipedia’s “dyspropterin” article, available under the CC BY-SA 4.0 licence.