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EA-4056

Structure via PubChem · Public domain (PubChem)

EntityQ51054289· pop 6· linked from 456 articles

EA-4056 is a deadly carbamate nerve agent. It is lethal because it inhibits acetylcholinesterase. Inhibition causes an overly high accumulation of acetylcholine between the nerve and muscle cells. This paralyzes the muscles by preventing their relaxation. The paralyzed muscles include those used for breathing.

Chemical data

Formula
C31H52Br2N6O4
Molecular weight
732.6 g/mol
IUPAC name
[3-(dimethylcarbamoyloxy)-2-pyridinyl]methyl-[9-[[3-(dimethylcarbamoyloxy)-2-pyridinyl]methyl-dimethylazaniumyl]nonyl]-dimethylazanium dibromide
SMILES
CN(C)C(=O)OC1=C(N=CC=C1)C[N+](C)(C)CCCCCCCCC[N+](C)(C)CC2=C(C=CC=N2)OC(=O)N(C)C.[Br-].[Br-]
InChIKey
AQIHLGWYYFRMKZ-UHFFFAOYSA-L
Polar surface area
84.9 Ų
H-bond donors
0
H-bond acceptors
8
Formal charge
0

via PubChem

Wikidata facts

Mass
730.241678344
Show 3 more facts
canonical SMILES
CN(C)C(=O)OC1=C(N=CC=C1)C[N+](C)(C)CCCCCCCCC[N+](C)(C)CC2=C(C=CC=N2)OC(=O)N(C)C.[Br-].[Br-]
Commons category
EA-4056
chemical formula
C₃₁H₅₂Br₂N₆O₄

via Wikidata · CC0

~4 min read

Encyclopedic overview

5 sections
Contents
  • Lethality
  • Properties
  • Synthesis
  • See also
  • References

{{Chembox | Name = EA-4056 | ImageFile = EA_4056.png | ImageClass = skin-invert-image | ImageFile1 = EA-4056_3D_structure.png | ImageClass1 = bg-transparent | OtherNames = | IUPACName = 1,9-Bis[methyl-2(3-dimethylcarbamoxypyridyl)methylamino]nonane dimethobromide | PIN = N1,N9-Bis({3-[(dimethylcarbamoyl)oxy]pyridin-2-yl}methyl)-N1,N1,N9,N9-tetramethylnonane-1,9-bis(aminium) dibromide | SystematicName = | Section1 = | Section2 = | Section3 = | Section4 = | Section5 = | Section6 = }}

EA-4056 is a deadly carbamate nerve agent. It is lethal because it inhibits acetylcholinesterase. Inhibition causes an overly high accumulation of acetylcholine between the nerve and muscle cells. This paralyzes the muscles by preventing their relaxation. The paralyzed muscles include those used for breathing.

Excerpted from Wikipedia’s “EA-4056” article, available under the CC BY-SA 4.0 licence.

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