enterotoxin
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An enterotoxin is a protein exotoxin released by a microorganism that targets the intestines. They can be chromosomally or plasmid encoded. They are heat labile (> 60 °C), of low molecular weight and water-soluble. Enterotoxins are frequently cytotoxic and kill cells by altering the apical membrane permeability of the mucosal (epithelial) cells of the intestinal wall. They are mostly pore-forming toxins (mostly chloride pores), secreted by bacteria, that assemble to form pores in cell membranes. This causes the cells to die.
Key facts
- Protein family.Symbol
- Stap_Strp_tox_C
- Protein family.Name
- Staph/Strep enterotoxin, C terminal
- Protein family.image
- PDB 1uns EBI.jpg
- Protein family.caption
- identification of a secondary zinc-binding site in staphylococcal enterotoxin c2: implications for superantigen recognition
- Protein family.Pfam
- PF02876
- Protein family.Pfam_clan
- CL0386
- Protein family.InterPro
- IPR006123
- Protein family.PROSITE
- PDOC00250
- Protein family.SCOP
- 1se3
- Protein family.OPM family
- 364
- Protein family.OPM protein
- 1dyq
via Wikipedia infobox
~5 min read
Article
7 sectionsContents
- Clinical significance
- Classification and 3D structures
- Bacterial
- Viral
- See also
- References
- External links
An enterotoxin is a protein exotoxin released by a microorganism that targets the intestines. They can be chromosomally or plasmid encoded. They are heat labile (> 60 °C), of low molecular weight and water-soluble. Enterotoxins are frequently cytotoxic and kill cells by altering the apical membrane permeability of the mucosal (epithelial) cells of the intestinal wall. They are mostly pore-forming toxins (mostly chloride pores), secreted by bacteria, that assemble to form pores in cell membranes. This causes the cells to die.
== Clinical significance ==