FBXO6
Sign in to saveAlso known as FBG2, FBS2, FBX6, Fbx6b, F-box protein 6
F-box only protein 6 is a protein that in humans is encoded by the FBXO6 gene.
Gene data
FBXO6- Name
- F-box protein 6
- Type
- protein-coding
- Position
- 11,664,141–11,674,354 (+)
- Aliases
- FBG2, FBS2, FBX6, Fbx6b
- Ensembl
- ENSG00000116663
- RefSeq RNA
- NM_018438.6, XM_005263448.6, XM_005263449.6, XM_005263451.6, XM_011541232.4
- RefSeq protein
- NP_060908.1, XP_005263505.1, XP_005263506.1, XP_005263508.1, XP_011539534.1
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
F-box protein 6
- Symbol
- FBXO6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:11,664,141-11,674,354
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
F-box only protein 6 is a protein that in humans is encoded by the FBXO6 gene.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle.
Excerpted from Wikipedia’s “FBXO6” article, available under the CC BY-SA 4.0 licence.