Ferredoxin 2
Sign in to saveAlso known as Ferredoxin-1-like protein, ferredoxin 1 like, FDX2, adrenodoxin-like protein, mitochondrial, FDX1L, ferredoxin-2, mitochondrial
Ferredoxin 2 is a protein that in humans is encoded by the FDX2 gene. It participates in heme A synthesis and iron-sulphur protein synthesis.
In the Vinony graph
Vinony's link graph records 3 inbound references to Ferredoxin 2, and connects out to Q180686, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Vinony links it to 5 Wikipedia language editions.
Protein · UniProt
Ferredoxin-2, mitochondrial
- Gene
- FDX2
- Organism
- Homo sapiens (Human)
- Length
- 183 aa
- Molecular mass
- 19,521 Da
- Evidence
- 1: Evidence at protein level
Electron donor, of the core iron-sulfur cluster (ISC) assembly complex, that acts to reduce the persulfide into sulfide during [2Fe-2S] clusters assembly on the scaffolding protein ISCU (PubMed:28001042). The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis (By similarity). This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner (By similarity…
Swiss-Prot (reviewed) · via UniProt
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Ferredoxin 2 is a protein that in humans is encoded by the FDX2 gene. It participates in heme A synthesis and iron-sulphur protein synthesis.
Mutations in FDX2 cause mitochondrial myopathy.
Excerpted from Wikipedia’s “Ferredoxin 2” article, available under the CC BY-SA 4.0 licence.