Structure via PubChem · Public domain (PubChem)
folpet
Sign in to saveAlso known as N-(trichloromethanesulfenyl)phthalimide, N-(trichloromethanesulphenyl)phthalimide, trichloromethylthiophthalimide, N-(trichloromethylthio)phthalimide
Folpet is the tradename for the organic compound with the formula C6H4(CO)2NSCCl3. It is a fungicide derived from phthalimide (C6H4(CO)2N-) and trichloromethylsulfenyl chloride. The compound is white although commercial samples can appear brownish. It is structurally related to Captan, which is also a trichloromethylsulfenyl-containing fungicide.
Chemical data
- Formula
- C9H4Cl3NO2S
- Molecular weight
- 296.6 g/mol
- IUPAC name
- 2-(trichloromethylsulfanyl)isoindole-1,3-dione
- SMILES
- C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl
- InChIKey
- HKIOYBQGHSTUDB-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 62.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
201 papers- Folpet (Pesticides).Food safety (Tokyo, Japan) · 2017
- Carcinogenic mode of action of folpet in mice and evaluation of its relevance to humans.Critical reviews in toxicology · 2010
- Folpet induces mitochondrial dysfunction and ROS-mediated apoptosis in mouse Sertoli cells.Pesticide biochemistry and physiology · 2021
- Peer review of the pesticide risk assessment of the active substance folpet.EFSA journal. European Food Safety Authority · 2023
- Folpet promotes apoptosis of bovine mammary epithelial cells via disruption of redox homeostasis and activation of MAPK cascades.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2023
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 294.903
Show 4 more facts
- chemical formula
- C₉H₄Cl₃NO₂S
- canonical SMILES
- C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl
- subject has role
- carcinogen
- Commons category
- Folpet
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Resistance
- References
Folpet is the tradename for the organic compound with the formula C6H4(CO)2NSCCl3. It is a fungicide derived from phthalimide (C6H4(CO)2N-) and trichloromethylsulfenyl chloride. The compound is white although commercial samples can appear brownish. It is structurally related to Captan, which is also a trichloromethylsulfenyl-containing fungicide.
==Resistance== folpet resistance is still unheard of due to its multiple effects. However, in 2001 some degree of cross-resistance was reported in iprodione-resistant South African Botrytis cinerea on grape.
Excerpted from Wikipedia’s “folpet” article, available under the CC BY-SA 4.0 licence.