Structure via PubChem · Public domain (PubChem)
formylthiophene
Sign in to saveAlso known as 2-thienylaldehyde, alpha-formylthiophene, thiophene-2-carboxaldehyde, 2-thiophenecarboxaldehyde, 2-formylthiophene, thiophene-2-aldehyde, T2A
Thiophene-2-carboxaldehyde is an organosulfur compound with the formula C4H3SCHO. It is one of two isomeric thiophenecarboxaldehydes. It is a colorless liquid that often appears amber after storage. It is versatile precursor to many drugs including eprosartan, Azosemide, and Teniposide.
Chemical data
- Formula
- C5H4OS
- Molecular weight
- 112.15 g/mol
- IUPAC name
- thiophene-2-carbaldehyde
- SMILES
- C1=CSC(=C1)C=O
- InChIKey
- CNUDBTRUORMMPA-UHFFFAOYSA-N
- XLogP
- 1
- Polar surface area
- 45.3 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 111.998285748
Show 3 more facts
- chemical formula
- C₅H₄OS
- canonical SMILES
- C1=CSC(=C1)C=O
- Commons category
- Thiophene-2-carbaldehyde
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Preparation
- References
Thiophene-2-carboxaldehyde is an organosulfur compound with the formula C4H3SCHO. It is one of two isomeric thiophenecarboxaldehydes. It is a colorless liquid that often appears amber after storage. It is versatile precursor to many drugs including eprosartan, Azosemide, and Teniposide.
==Preparation== It can be prepared from thiophene by the Vilsmeier reaction. Alternatively, it is prepared from chloromethylation of thiophene.
Excerpted from Wikipedia’s “formylthiophene” article, available under the CC BY-SA 4.0 licence.