gamendazole
Sign in to saveAlso known as trans-3-(1-benzyl-6-(trifluoromethyl)-1H-indazol-3-yl)acrylic acid
Gamendazole is a drug candidate for male contraception. It is an indazole carboxylic acid derived from lonidamine (LND). It has been shown to reduce fertility in male rats without affecting testosterone levels, but human clinical trials have not been started.
Wikidata facts
- Mass
- 414.014968
Show 4 more facts
- chemical formula
- C₁₈H₁₁Cl₂F₃N₂O₂
- Commons category
- Gamendazole
- canonical SMILES
- C1=CC2=C(C=C1C(F)(F)F)N(N=C2C=CC(=O)O)CC3=C(C=C(C=C3)Cl)Cl
- isomeric SMILES
- C1=CC2=C(C=C1C(F)(F)F)N(N=C2/C=C/C(=O)O)CC3=C(C=C(C=C3)Cl)Cl
Sources (1)
via Wikidata · CC0
~2 min read
Article
2 sectionsContents
- Rat studies
- References
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Gamendazole is a drug candidate for male contraception. It is an indazole carboxylic acid derived from lonidamine (LND). It has been shown to reduce fertility in male rats without affecting testosterone levels, but human clinical trials have not been started.