GC-content
Sign in to savethumb|400px|Nucleotide bonds showing AT and GC pairs. Arrows point to the hydrogen bonds. In molecular biology and genetics, GC-content (or G+C content or guanine-cytosine content) is the percentage of nitrogenous bases in a DNA or RNA molecule that are either guanine (G) or cytosine (C). This measure indicates the proportion of G and C bases out of an implied four total bases, also including adenine and thymine in DNA and adenine and uracil in RNA.
~8 min read
Article
13 sectionsContents
- Structure
- Determination
- Genomic content
- Within-genome variation
- Coding sequences
- Among-genome variation
- Applications
- Molecular biology
- Systematics
- Software tools
- See also
- References
- External links
thumb|400px|Nucleotide bonds showing AT and GC pairs. Arrows point to the hydrogen bonds. In molecular biology and genetics, GC-content (or G+C content or guanine-cytosine content) is the percentage of nitrogenous bases in a DNA or RNA molecule that are either guanine (G) or cytosine (C). This measure indicates the proportion of G and C bases out of an implied four total bases, also including adenine and thymine in DNA and adenine and uracil in RNA.
GC-content may be given for a certain fragment of DNA or RNA or for an entire genome. When it refers to a fragment, it may denote the GC-content of an individual gene or section of a gene (domain), a group of genes or gene clusters, a non-coding region, or a synthetic oligonucleotide such as a primer.