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glutaral

Structure via PubChem · Public domain (PubChem)

EntityQ416475· pop 31· linked from 89 articles

Also known as Glutaric dialdehyde, 1,5-Pentanedial, Glutardialdehyde, 1,5-Pentanedione, 1,3-Diformylpropane, Glutaric acid dialdehyde, Glutaraldehyde

Glutaraldehyde is an organic compound with the formula . The molecule consists of a five carbon chain doubly terminated with formyl (CHO) groups. It is usually used as a solution in water, and such solutions exists as a collection of hydrates, cyclic derivatives, and condensation products, several of which interconvert. Because the molecule has two aldehyde functional groups, glutaraldehyde (and its hydrates) can crosslink substances with primary amine groups, through condensation. Crosslinking can rigidify and deactivate proteins and other molecules that are critical for normal biological fun

Chemical data

Formula
C5H8O2
Molecular weight
100.12 g/mol
IUPAC name
pentanedial
SMILES
C(CC=O)CC=O
InChIKey
SXRSQZLOMIGNAQ-UHFFFAOYSA-N
XLogP
-0.5
Polar surface area
34.1 Ų
H-bond donors
0
H-bond acceptors
2
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Research

7,556 papers

via PubMed

Wikidata facts

Subclass of
aldehydes
Mass
100.052
Show 12 more facts
ceiling exposure limit
0.8
chemical formula
C₅H₈O₂
NIOSH Pocket Guide ID
0301
density
1.10
melting point
-21
boiling point
212
vapor pressure
17
canonical SMILES
C(CC=O)CC=O
World Health Organisation international non-proprietary name
glutaral
Commons category
Glutaraldehyde
subject has role
essential medicine
MCN code
2912.19.12
Sources (4)

via Wikidata · CC0

~6 min read

Encyclopedic overview

14 sections
Contents
  • Uses
  • Biochemistry
  • Material science
  • Medical
  • Clinical uses
  • Dermatological uses
  • Other uses
  • Aquaria
  • Safety
  • Production and reactions
  • Production
  • Reactions
  • References
  • External links

Glutaraldehyde is an organic compound with the formula . The molecule consists of a five carbon chain doubly terminated with formyl (CHO) groups. It is usually used as a solution in water, and such solutions exists as a collection of hydrates, cyclic derivatives, and condensation products, several of which interconvert. Because the molecule has two aldehyde functional groups, glutaraldehyde (and its hydrates) can crosslink substances with primary amine groups, through condensation. Crosslinking can rigidify and deactivate proteins and other molecules that are critical for normal biological function, such as DNA, and so glutaraldehyde solutions are effective biocides and fixatives. It is sold under the brandnames Cidex and Glutaral. As a disinfectant, it is used to sterilize surgical instruments.

==Uses==

Excerpted from Wikipedia’s “glutaral” article, available under the CC BY-SA 4.0 licence.

Gallery (7)