GPIHBP1
Sign in to saveAlso known as GPI-HBP1, HYPL1D, glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 (GPI-HBP1) also known as high density lipoprotein-binding protein 1 is a protein that in humans is encoded by the GPIHBP1 gene.
Gene data
GPIHBP1- Name
- glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
- Type
- protein-coding
- Position
- 143,213,019–143,217,172 (+)
- Aliases
- GPI-HBP1, HYPL1D
- Ensembl
- ENSG00000277494
- RefSeq RNA
- NM_001301772.2, NM_178172.6
- RefSeq protein
- NP_001288701.1, NP_835466.2
This gene encodes a capillary endothelial cell protein that facilitates the lipolytic processing of triglyceride-rich lipoproteins. The encoded protein is a glycosylphosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly6) family. This protein plays a major role in transporting lipoprotein lipase (LPL) from the subendothelial spaces to the capillary lumen. Mutations in this gene are the cause of hyperlipoproteinemia, type 1D. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
- Symbol
- GPIHBP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:143,213,019-143,217,172
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 18651
- exact match
- identifiers.org/ncbigene/338328
- genomic end
- 144299044
- genomic start
- 143213218
- cytogenetic location
- 8q24.3
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 (GPI-HBP1) also known as high density lipoprotein-binding protein 1 is a protein that in humans is encoded by the GPIHBP1 gene.
==Function==