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Greg Winter

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Greg Winter

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Also known as Sir Gregory Paul Winter

British biochemist (born 1951)

AI overview

Greg Winter is a British biochemist born in 1951 who developed techniques for producing antibodies in the laboratory, which has had major applications in medicine and disease treatment. His work earned him a share of the Nobel Prize in Chemistry and represents an important advance in how scientists can create therapeutic proteins to fight illness.

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Type
Person
Gender
Male
Origin
United States
Active from
1944-02-23
Active to
2014-07-16
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Key facts

Preceded by
Baron Rees of Ludlow
Succeeded by
Dame Sally Davies
Born
Gregory Paul Winter , ( 1951-04-14 ) 14 April 1951 (age 75) , Leicester , Leicestershire , England
Website
LMB web page
Education
Royal Grammar School, Newcastle upon Tyne
Alma mater
Trinity College, Cambridge ( MA , PhD )
Known for
Cambridge Antibody Technology , Domantis , Bicycle Therapeutics , Antibody engineering
Awards
Colworth Medal (1986), EMBO Member (1987) , Louis-Jeantet Prize for Medicine (1989) , Knight Bachelor (2004), Royal Medal (2011), Prince Mahidol Award (2016) , Nobel Prize in Chemistry (2018), Copley Medal (2024)
Fields
Biochemistry
Institutions
University of Cambridge , Laboratory of Molecular Biology , Imperial College London
Thesis
The amino acid sequence of tryptophanyl tRNA synthetase from Bacillus stearothermophilus (1977)
Doctoral advisor
Brian S. Hartley

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Wikidata facts

Image
Gregory Winter, 2016 (cropped).jpg
Show 3 more facts
date of birth
1951-04-14
Commons category
Gregory Winter
name in native language
Greg Winter
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Article

Sir Gregory Paul Winter (born 14 April 1951) is a Nobel Prize–winning British molecular biologist best known for his work on the therapeutic use of monoclonal antibodies. His research career has been based almost entirely at the MRC Laboratory of Molecular Biology and the MRC Centre for Protein Engineering, in Cambridge, England.

He is credited with the invention of techniques to both humanize (1986) and, later, to fully humanize using phage display, antibodies for therapeutic uses. Previously, antibodies had been derived from mice, which made them difficult to use in human therapeutics because the human immune system had anti-mouse reactions to them. For these developments Winter was awarded the 2018 Nobel Prize in Chemistry along with George Smith and Frances Arnold.

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