hemangioblast
Sign in to saveHemangioblasts are the multipotent precursor cells that can differentiate into both hematopoietic and endothelial cells. In the mouse embryo, the emergence of blood islands in the yolk sac at embryonic day 7 marks the onset of hematopoiesis. From these blood islands, the hematopoietic cells and vasculature are formed shortly after. Hemangioblasts are the progenitors that form the blood islands. To date, the hemangioblast has been identified in human, mouse and zebrafish embryos.
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Within Vinony's link graph, hemangioblast is referenced by 15 other articles, and connects out to Latin, circulatory system and infant.
It is catalogued under topics including Cell biology and Stem cells.
Its subject is documented across 5 Wikipedia language editions.
Research
764 papers- Hemangioblast, hemogenic endothelium, and primitive versus definitive hematopoiesis.Experimental hematology · 2017
- Hemangioblast: an in vitro phantom.Wiley interdisciplinary reviews. Developmental biology · 2012
- The hemangioblast: from concept to authentication.Anatomical record (Hoboken, N.J. : 2007) · 2011
- The hemangioblast: cradle to clinic.Experimental hematology · 2004
- Hemangioblast does exist.Leukemia research · 2008
via PubMed
Wikidata facts
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- Commons category
- Hemangioblasts
- native label
- hemangioblastus
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Encyclopedic overview
6 sectionsContents
- Adult hemangioblast
- History
- Isolation
- See also
- References
- External links
Hemangioblasts are the multipotent precursor cells that can differentiate into both hematopoietic and endothelial cells. In the mouse embryo, the emergence of blood islands in the yolk sac at embryonic day 7 marks the onset of hematopoiesis. From these blood islands, the hematopoietic cells and vasculature are formed shortly after. Hemangioblasts are the progenitors that form the blood islands. To date, the hemangioblast has been identified in human, mouse and zebrafish embryos.
Hemangioblasts have been first extracted from embryonic cultures and manipulated by cytokines to differentiate along either hematopoietic or endothelial route. It has been shown that these pre-endothelial/pre-hematopoietic cells in the embryo arise out of a phenotype CD34 population. It was then found that hemangioblasts are also present in the tissue of post-natal individuals, such as in newborn infants and adults.
Excerpted from Wikipedia’s “hemangioblast” article, available under the CC BY-SA 4.0 licence.