~4 min read
Encyclopedic overview
8 sectionsContents
- Classification according to amine precursor
- Addition of ammonia
- Addition of primary amines
- Addition of secondary amines: carbinolamines (hemiaminals) and bisaminomethanes
- Hemiaminal ethers
- Use in total synthesis
- See also
- References
thumb|right|120px|Generic hemiaminal
In organic chemistry, a hemiaminal (also carbinolamine) is a functional group or type of chemical compound that has a hydroxyl group and an amine attached to the same carbon atom: . R can be hydrogen or an alkyl group. Hemiaminals are intermediates in imine formation from an amine and a carbonyl by alkylimino-de-oxo-bisubstitution. Hemiaminals can be viewed as a blend of aminals and geminal diol. They are a special case of amino alcohols.
Excerpted from Wikipedia’s “hemiaminal” article, available under the CC BY-SA 4.0 licence.