Structure via PubChem · Public domain (PubChem)
HOT-2
Sign in to saveAlso known as 2,5-dimethoxy-4-(β-ethylthio)-N-hydroxyphenethylamine
HOT-2, also known as '4-ethylthio-2,5-dimethoxy-N-hydroxyphenethylamine or as N-hydroxy-2C-T-2', is a psychedelic drug of the phenethylamine, 2C, and HOT-x families. It is the N-hydroxy derivative of 2C-T-2. The drug is taken orally.
Chemical data
- Formula
- C12H19NO3S
- Molecular weight
- 257.35 g/mol
- IUPAC name
- N-[2-(4-ethylsulfanyl-2,5-dimethoxyphenyl)ethyl]hydroxylamine
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 257.108564468
Show 3 more facts
- canonical SMILES
- CCSc1cc(OC)c(cc1OC)CCNO
- chemical formula
- C₁₂H₁₉NO₃S
- Commons category
- HOT (hydroxylamine)
Sources (2)
via Wikidata · CC0
~2 min read
Article
13 sectionsContents
- Use and effects
- Interactions
- Chemistry
- Synthesis
- Analogues
- History
- Society and culture
- Legal status
- Canada
- United Kingdom
- See also
- References
- External links
HOT-2, also known as '4-ethylthio-2,5-dimethoxy-N-hydroxyphenethylamine or as N-hydroxy-2C-T-2', is a psychedelic drug of the phenethylamine, 2C, and HOT-x families. It is the N-hydroxy derivative of 2C-T-2. The drug is taken orally.
==Use and effects== In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists HOT-2's dose range as 10 to 18mg orally and its duration as 6 to 10hours. The drug's onset is 30 to 40minutes and peak effects occur after 2hours. HOT-2's properties are very similar to those of 2C-T-2, which has a dose of 12 to 25mg orally, a duration of 6 to 8hours, and an onset of less than 1hour with a time to peak of 1 to 2hours. HOT-2 may act as a prodrug of 2C-T-2.