Skip to content
ไอดีบีโนน

Structure via PubChem · Public domain (PubChem)

EntityQ4197874· pop 15· linked from 16 articles

ไอดีบีโนน

Sign in to save

Also known as 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, 2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone, 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone, CV 2619, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone, BRN 2001459, 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone

Idebenone, sold under the brand name Raxone among others, is a medication that was initially developed by Takeda Pharmaceutical Company for the treatment of Alzheimer's disease and other cognitive defects. This has been met with limited success. The Swiss company Santhera Pharmaceuticals has started to investigate it for the treatment of neuromuscular diseases. In 2010, early clinical trials for the treatment of Friedreich's ataxia and Duchenne muscular dystrophy have been completed. the drug is not approved for these indications in North America or Europe. It is approved by the European Medic

Chemical data

Formula
C19H30O5
Molecular weight
338.4 g/mol
IUPAC name
2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
SMILES
CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO
InChIKey
JGPMMRGNQUBGND-UHFFFAOYSA-N
XLogP
4.3
Polar surface area
72.8 Ų
H-bond donors
1
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Approved
Molecule type
Small molecule
First approval
2015
Indications
MELAS, primary progressive multiple sclerosis, attention deficit hyperactivity disorder, non-alcoholic fatty liver disease

via ChEMBL · EBI

Wikidata facts

Has part
carbon
Mass
338.209324
Has use
medication
Show 6 more facts
chemical formula
C₁₉H₃₀O₅
canonical SMILES
CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO
World Health Organisation international non-proprietary name
idebenone
defined daily dose
0.9
subject has role
antioxidant
Commons category
Idebenone
Sources (6)

via Wikidata · CC0