iodoxamic acid

Chemical data

Formula

C26H26I6N2O10

Molecular weight

1287.9 g/mol

IUPAC name

3-[3-[2-[2-[2-[3-(3-carboxy-2,4,6-triiodoanilino)-3-oxopropoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-2,4,6-triiodobenzoic acid

SMILES

C1=C(C(=C(C(=C1I)NC(=O)CCOCCOCCOCCOCCC(=O)NC2=C(C=C(C(=C2I)C(=O)O)I)I)I)C(=O)O)I

InChIKey

WWVAPFRKZMUPHZ-UHFFFAOYSA-N

XLogP

4.2

Polar surface area

170 Ų

H-bond donors

4

H-bond acceptors

10

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

First approval

1982

Admin. routes

parenteral

via ChEMBL · EBI

• Biotransformation of ioglycamic acid, iodoxamic acid and iotroxic acid in man.Investigative radiology · 1976
• Pharmacokinetics of iodoxamic acid in rhesus monkey: biliary excretion, plasma protein binding, and enterophepatic circulation.Journal of pharmaceutical sciences · 1978
• Kinetics of drug-drug interactions: biliary excretion of iodoxamic acid and iopanoic acid in rhesus monkeys.Journal of pharmaceutical sciences · 1979
• Gastrointestinal radiology. Pharmacokinetics of iopanoate and iodoxamate in rhesus monkeys.Investigative radiology · 1980
• [Pharmacology of iotroxic acid, a new intravenous cholangiographic agent. II. Experimental animal study of side effects].Arzneimittel-Forschung · 1978

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

1287.586

via Wikidata · CC0