Skip to content
katanosin

Structure via PubChem · Public domain (PubChem)

EntityQ910540· pop 9· linked from 2 articles

Also known as katanosin A

Katanosins are a group of antibiotics (also known as lysobactins). They are natural products with strong antibacterial potency. So far, katanosin A and katanosin B (lysobactin) have been described.

Chemical data

Formula
C58H97N15O17
Molecular weight
1276.5 g/mol
IUPAC name
2-amino-N-[1-[[6-(2-amino-1-hydroxy-2-oxoethyl)-15-butan-2-yl-18-[3-(diaminomethylideneamino)propyl]-12-(1-hydroxyethyl)-3-(hydroxymethyl)-24-(1-hydroxy-2-methylpropyl)-21-(2-methylpropyl)-2,5,8,11,14,17,20,23,26-nonaoxo-28-phenyl-1-oxa-4,7,10,13,16,19,22,25-octazacyclooctacos-27-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide
SMILES
CCC(C)C1C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)OC(C(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN=C(N)N)CC(C)C)C(C(C)C)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)N)C2=CC=CC=C2)CO)C(C(=O)N)O)C(C)O
InChIKey
KQMKBWMQSNKASI-UHFFFAOYSA-N
XLogP
0.5
Polar surface area
532 Ų
H-bond donors
18
H-bond acceptors
19
Formal charge
0

via PubChem

Wikidata facts

Mass
1275.718687
Show 2 more facts
chemical formula
C₅₈H₉₇N₁₅O₁₇
canonical SMILES
CCC(C)C1C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)OC(C(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN=C(N)N)CC(C)C)C(C(C)C)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)N)C2=CC=CC=C2)CO)C(C(=O)N)O)C(C)O
Sources (1)

via Wikidata · CC0

~2 min read

Encyclopedic overview

5 sections
Contents
  • Sources
  • Structure
  • Biological activity
  • Chemical synthesis
  • References

Katanosins are a group of antibiotics (also known as lysobactins). They are natural products with strong antibacterial potency. So far, katanosin A and katanosin B (lysobactin) have been described.

==Sources== Katanosins have been isolated from the fermentation broth of microorganisms, such as Cytophaga. or the Gram-negative bacterium Lysobacter sp.

Excerpted from Wikipedia’s “katanosin” article, available under the CC BY-SA 4.0 licence.

Available in 9 languages

via Wikidata sitelinks · CC0