keloid
Sign in to saveAlso known as keloid formation, Keloid of Alibert
Keloid, also known as keloid disorder and keloidal scar, is the formation of a type of scar which, depending on its maturity, is composed mainly of either type III (early) or type I (late) collagen. It is a result of an overgrowth of granulation tissue (collagen type III) at the site of a healed skin injury, which is then slowly replaced by collagen type I. Keloids are firm, rubbery lesions or shiny, fibrous nodules, and can vary from pink to the color of the person's skin or red to dark brown. A keloid scar is benign and not contagious, but sometimes accompanied by severe itchiness, pain, and
Key facts
- Medical condition (new).name
- Keloid
- Medical condition (new).image
- Keloid, Post Surgical.JPG
- Medical condition (new).caption
- Bulky keloid forming at the site of abdominal surgery
- Medical condition (new).field
- Dermatology
- Medical condition (new).onset
- scar formation
- Medical condition (new).risks
- Sub-Saharan African, Asian or Latin American ancestry
via Wikipedia infobox
Research
7,665 papers- Characterization of the skin keloid microenvironment.Cell communication and signaling : CCS · 2023
- Keloid and Hypertrophic Scars Are the Result of Chronic Inflammation in the Reticular Dermis.International journal of molecular sciences · 2017
- Schwann cells contribute to keloid formation.Matrix biology : journal of the International Society for Matrix Biology · 2022
- Pathogenesis, attenuation, and treatment strategies for keloid management.Tissue & cell · 2025
- Histopathological differential diagnosis of keloid and hypertrophic scar.The American Journal of dermatopathology · 2004
via PubMed
Wikidata facts
- Image
- Keloid -1.jpg
Show 4 more facts
- Commons category
- Keloid
- ICD-9-CM
- 701.4
- NCI Thesaurus ID
- C3145
- exact match
- purl.obolibrary.org/obo/HP_0010562
via Wikidata · CC0
~13 min read
Article
11 sectionsContents
- Signs and symptoms
- Location
- Cause
- Genetics
- Pathology
- Treatments
- Epidemiology
- History
- References
- Further reading
- External links
Keloid, also known as keloid disorder and keloidal scar, is the formation of a type of scar which, depending on its maturity, is composed mainly of either type III (early) or type I (late) collagen. It is a result of an overgrowth of granulation tissue (collagen type III) at the site of a healed skin injury, which is then slowly replaced by collagen type I. Keloids are firm, rubbery lesions or shiny, fibrous nodules, and can vary from pink to the color of the person's skin or red to dark brown. A keloid scar is benign and not contagious, but sometimes accompanied by severe itchiness, pain, and changes in texture. In severe cases, it can affect the movement of the skin. In the United States, keloid scars are seen 15 times more frequently in people of sub-Saharan African descent than in people of European descent. There is a higher tendency to develop a keloid among those with a family history of keloids and people between the ages of 10 and 30 years.
Keloids should not be confused with hypertrophic scars, which are raised scars that do not grow beyond the boundaries of the original wound.