KLHDC3

Also known as PEAS, dJ20C7.3, kelch domain containing 3

Kelch domain-containing protein 3 is a protein that in humans is encoded by the KLHDC3 gene.

Gene data

KLHDC3

Name: kelch domain containing 3
Type: protein-coding
Position: 43,014,103–43,021,298 (+)
Aliases: PEAS, dJ20C7.3
Ensembl: ENSG00000124702
RefSeq RNA: NM_001242872.1, NM_057161.4, NR_040101.2, XM_047418163.1, XM_047418164.1
RefSeq protein: NP_476502.1, XP_047274119.1, XP_047274120.1, XP_054210163.1, XP_054210164.1

The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2, a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to be expressed specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasma and meiotic chromatin, suggesting that this gene may be involved in meiotic recombination. [provided by RefSeq, Jun 2012].

Gene Ontology

Biological process

reciprocal meiotic recombination

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Article

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References
Further reading

Kelch domain-containing protein 3 is a protein that in humans is encoded by the KLHDC3 gene.

The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2 (RAG2), a protein involved in the activation of the V(D)J recombination. This gene is found to express specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasm and meiotic chromatin, which suggests that this gene may be involved in meiotic recombination.