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(+)-L-alliin

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(+)-L-alliin

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Also known as (2R)-2-amino-3-[(S)-prop-2-enylsulfinyl]propanoic acid, (S)-S-Allyl-L-cysteine sulfoxide, (+)-Alliin

Alliin is a sulfoxide that is a natural constituent of fresh garlic. It is a derivative of the amino acid cysteine. When fresh garlic is chopped or crushed, the enzyme alliinase converts alliin into allicin, which is responsible for the aroma of fresh garlic. Allicin and other thiosulfinates in garlic are unstable and form a number of other compounds, such as diallyl sulfide (DAS), diallyl disulfide (DADS) and diallyl trisulfide (DAT), dithiins and ajoene. Garlic powder is not a source of alliin, nor is fresh garlic upon maceration, since the enzymatic conversion to allicin takes place in the

Chemical data

Formula
C6H11NO3S
Molecular weight
177.22 g/mol
IUPAC name
(2R)-2-amino-3-[(S)-prop-2-enylsulfinyl]propanoic acid
SMILES
C=CC[S@](=O)C[C@@H](C(=O)O)N
InChIKey
XUHLIQGRKRUKPH-DYEAUMGKSA-N
XLogP
-3.5
Polar surface area
99.6 Ų
H-bond donors
2
H-bond acceptors
5
Formal charge
0

via PubChem

~2 min read

Encyclopedic overview

3 sections
Contents
  • Chemical synthesis
  • Medical exploration
  • References

Alliin is a sulfoxide that is a natural constituent of fresh garlic. It is a derivative of the amino acid cysteine. When fresh garlic is chopped or crushed, the enzyme alliinase converts alliin into allicin, which is responsible for the aroma of fresh garlic. Allicin and other thiosulfinates in garlic are unstable and form a number of other compounds, such as diallyl sulfide (DAS), diallyl disulfide (DADS) and diallyl trisulfide (DAT), dithiins and ajoene. Garlic powder is not a source of alliin, nor is fresh garlic upon maceration, since the enzymatic conversion to allicin takes place in the order of seconds.

Alliin was the first natural product found to have both carbon- and sulfur-centered stereochemistry.

Excerpted from Wikipedia’s “(+)-L-alliin” article, available under the CC BY-SA 4.0 licence.

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