lactone

Also known as lactones

Lactones are cyclic carboxylic esters. They are derived from the corresponding hydroxycarboxylic acids by esterification. They can be saturated or unsaturated.

Research

213,418 papers

Biosynthesis and chemical diversity of β-lactone natural products.Natural product reports · 2019
Macrocyclic lactone resistance in Dirofilaria immitis: risks for prevention of heartworm disease.International journal for parasitology · 2021
Phytohabitols A-C, δ-Lactone-Terminated Polyketides from an Actinomycete of the Genus Phytohabitans.Journal of natural products · 2022
Synthetic studies of (23S,25R)-1α,25-dihydroxyvitamin D(3) 26,23-lactone (calcitriol lactone) and its derivatives.The Journal of steroid biochemistry and molecular biology · 2018
14- and 15-membered lactone macrolides and their analogues and hybrids: structure, molecular mechanism of action and biological activity.European journal of medicinal chemistry · 2019

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Wikidata facts

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Commons category: Lactones
SMARTS notation: [CR1](=[OX1])[OR1]

Sources (2)

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Article

14 sections

Contents

Nomenclature
Etymology
Occurrence
Synthesis
Reactions
Hydrolysis and aminolysis
Reduction
Polymerization
Uses
Flavors and fragrances
Plastics
Dilactones
See also
References and notes

Lactones are cyclic carboxylic esters. They are derived from the corresponding hydroxycarboxylic acids by esterification. They can be saturated or unsaturated.

Lactones are formed by lactonization, the intramolecular esterification of the corresponding hydroxycarboxylic acids.