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Lassa fever

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Also known as Lassa hemorrhagic fever, LHF, LF

viral disease

Key facts

Other names
Lassa hemorrhagic fever
Specialty
Infectious disease
Symptoms
Fever , headaches , bleeding
Complications
Partial or complete, temporary or permanent hearing loss
Usual onset
1–3 weeks following exposure
Causes
Lassa virus
Risk factors
Exposure to rodents in West Africa
Diagnostic method
Laboratory testing
Differential diagnosis
Ebola , malaria , typhoid fever
Treatment
Supportive
Prognosis
~1% risk of death with treatment
Frequency
400,000 cases per year
Deaths
5,000 deaths per year

via Wikipedia infobox

Research

1,882 papers

via PubMed

Wikidata facts

Image
Lassa virus.JPG
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NCI Thesaurus ID
C128418
ICD-9-CM
078.89
Commons category
Lassa fever
minimal incubation period in humans
3
maximal incubation period in humans
17
time of discovery or invention
1950-00-00
Sources (6)

via Wikidata · CC0

~20 min read

Article

Lassa fever, also known as Lassa hemorrhagic fever, is a type of viral hemorrhagic fever caused by the Lassa virus. Many of those infected by the virus do not develop symptoms. When symptoms occur, they typically include fever, weakness, headaches, vomiting, and muscle pains. Less commonly there may be bleeding from the mouth or gastrointestinal tract. The risk of death once infected is about one percent and frequently occurs within two weeks of the onset of symptoms. Of those who survive, about a quarter have hearing loss, which improves within three months in about half of these cases.

Lassa fever is usually initially spread to humans via contact with the urine or feces of an infected multimammate mouse. Spread can then occur via direct contact between people. Diagnosis based on symptoms is difficult. Confirmation is by laboratory testing to detect the virus's RNA, antibodies for the virus, or the virus itself in cell culture. Other conditions that may present similarly include Ebola, malaria, typhoid fever, and yellow fever. The Lassa virus is a member of the Arenaviridae family of viruses.

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