Key facts
- Other names
- Lassa hemorrhagic fever
- Specialty
- Infectious disease
- Symptoms
- Fever , headaches , bleeding
- Complications
- Partial or complete, temporary or permanent hearing loss
- Usual onset
- 1–3 weeks following exposure
- Causes
- Lassa virus
- Risk factors
- Exposure to rodents in West Africa
- Diagnostic method
- Laboratory testing
- Differential diagnosis
- Ebola , malaria , typhoid fever
- Treatment
- Supportive
- Prognosis
- ~1% risk of death with treatment
- Frequency
- 400,000 cases per year
- Deaths
- 5,000 deaths per year
via Wikipedia infobox
Research
1,882 papers- Lassa fever - the road ahead.Nature reviews. Microbiology · 2023
- Lassa fever research priorities: towards effective medical countermeasures by the end of the decade.The Lancet. Infectious diseases · 2024
- Lassa fever diagnostics: past, present, and future.Current opinion in virology · 2019
- Lassa Fever in Travelers from West Africa, 1969-2016.Emerging infectious diseases · 2019
- Lassa fever.Journal of the American Academy of Nurse Practitioners · 2002
via PubMed
Wikidata facts
- Image
- Lassa virus.JPG
Show 7 more facts
- exact match
- www.orpha.net/ORDO/Orphanet_99824
- NCI Thesaurus ID
- C128418
- ICD-9-CM
- 078.89
- Commons category
- Lassa fever
- minimal incubation period in humans
- 3
- maximal incubation period in humans
- 17
- time of discovery or invention
- 1950-00-00
via Wikidata · CC0
~20 min read
Article
Lassa fever, also known as Lassa hemorrhagic fever, is a type of viral hemorrhagic fever caused by the Lassa virus. Many of those infected by the virus do not develop symptoms. When symptoms occur, they typically include fever, weakness, headaches, vomiting, and muscle pains. Less commonly there may be bleeding from the mouth or gastrointestinal tract. The risk of death once infected is about one percent and frequently occurs within two weeks of the onset of symptoms. Of those who survive, about a quarter have hearing loss, which improves within three months in about half of these cases.
Lassa fever is usually initially spread to humans via contact with the urine or feces of an infected multimammate mouse. Spread can then occur via direct contact between people. Diagnosis based on symptoms is difficult. Confirmation is by laboratory testing to detect the virus's RNA, antibodies for the virus, or the virus itself in cell culture. Other conditions that may present similarly include Ebola, malaria, typhoid fever, and yellow fever. The Lassa virus is a member of the Arenaviridae family of viruses.