leonurine
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Leonurine (also known as SCM-198 in research) is a pseudoalkaloid that has been isolated from Leonotis leonurus, Leonotis nepetifolia, Leonurus japonicus, Leonurus cardiaca (motherwort), Leonurus sibiricus, as well as other plants of family Lamiaceae. Leonurine is easily extracted into water.
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Vinony's link graph records 6 inbound references to leonurine, and connects out to Gabriel synthesis, digital object identifier and chemical formula.
It is catalogued under topics including Alkaloids, Benzoate esters and Chembox image size set.
Vinony links it to 10 Wikipedia language editions.
Wikidata facts
- Mass
- 311.148121
Show 2 more facts
- chemical formula
- C₁₄H₂₁N₃O₅
- canonical SMILES
- COC1=CC(=CC(=C1O)OC)C(=O)OCCCCN=C(N)N
Sources (2)
via Wikidata · CC0
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Encyclopedic overview
5 sectionsContents
- Research
- Metabolites
- Chemical synthesis
- References
- Further reading
Leonurine (also known as SCM-198 in research) is a pseudoalkaloid that has been isolated from Leonotis leonurus, Leonotis nepetifolia, Leonurus japonicus, Leonurus cardiaca (motherwort), Leonurus sibiricus, as well as other plants of family Lamiaceae. Leonurine is easily extracted into water.
== Research == Leonurine weakly binds to multiple GABA receptor sites including the GABAA receptor. However, it shows much higher affinity as a 5-HT3A receptor antagonist. 5-HT3A antagonists have been shown to help prevent nausea and vomiting as well as the negative effects of serotonin in the gastrointestinal tract.
Excerpted from Wikipedia’s “leonurine” article, available under the CC BY-SA 4.0 licence.